We are testing a different way to expand the supply of donor lungs. Our EVLP service is founded on our mission to make a difference in lung transplantation.
Our model is designed to advance lung transplantation by centralizing EVLP services, removing the resource burden from the lung transplant centers. Our EVLP Specialists have an extensive clinical background and undergo intensive EVLP training.
We believe our EVLP service model may be an answer to the shortage of donor lungs. Lung transplant is the only life-saving therapy for patients with certain types of end stage lung disease. However, the current shortage of donor lungs means more than 200 candidates die each year awaiting a lung transplant.
EVLP is a process that allows lungs that may not otherwise have been used to be assessed outside of the body prior to transplant. During the EVLP process, lung function is continuously monitored and data are shared remotely with the transplant physician for real-time evaluation. This allows the transplant physician to receive all clinically relevant information about the lungs without having to be present in the EVLP procedure room. If the lungs are deemed suitable after EVLP by a transplant physician, the lungs are transplanted into a waiting clinical trial participant.
Lung Bioengineering initiates these centralized EVLP services by triaging notifications from either an OPO (organ procurement organization) or transplant center. At all times, an OPO controls the screening, procurement, allocation, and distribution of lungs. The transplant center retains full medical responsibility for approving the lung for transplant and transplanting it into the recipient.
USING TORONTO EVLP METHOD
CLOUD BASED COMMUNICATION
LIVE STREAMING VIDEO
Our clinical trial is based on the Toronto EVLP protocol which is the most widely used and most referenced method for EVLP. In this method, protective perfusion and ventilation strategies are used to gather additional information about the functionality of the lungs.
THE CASE MANAGEMENT EXCHANGE
The Case Management Exchange (CMX) is a clinical decision support system that gives transplant physicians access to data collected during the EVLP process. This allows the physician to make real-time assessments during perfusion in order to determine the acceptability of the lungs for transplant. In addition to standard clinical data to evaluate lung function, the CMX displays photographs, radiographs, and high-definition video of the procedure, including bronchoscopies. The CMX can be accessed via a secure, cloud-based software platform from wherever an internet connection is available. Combined with integrated live-streaming video, the CMX is designed to give transplant physicians confidence in assessing lungs for transplant, even from a remote location.
Please fill out the form below to request more information about our study and to find out how to get involved.